Reach Us +441902928240

The Motor Branch of the Median Nerve, a Rare Localization of Schwannoma

K. Slimane, M.A. Sbai, F. Elfeki and R. Maalla*

Faculty of Medicine, Plastic Reconstructive & Hand Surgery, La Rabta Teaching Hospital Center, Tunis, 1007, Tunisia

*Corresponding Author:
R. Maalla
Faculty of Medicine
Plastic Reconstructive & Hand Surgery
La Rabta Teaching Hospital Center
Tunis , 1007, Tunisia
Tel: 00216 98 406 224
E-mail: [email protected]

Received date: April 22, 2016; Accepted date: May 18, 2016; Published date: May 20, 2016

Citation: Slimane K, Sbai MA, Elfeki F, Maalla R (2016) The Motor Branch of the Median Nerve, a Rare Localization of Schwannoma. J Clin Exp Orthop 2:18. doi: 10.4172/2471-8416.100018

Copyright: © 2016 Slimane K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License,which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 
Visit for more related articles at Journal of Clinical & Experimental Orthopaedics

Abstract

Schwannoma is the most common benign tumor of peripheral nerve. Only 7% of schwannomas arise from the median nerve, and its localization in the motor branch is extremely rare. A 57-year old right-handed female presented with a carpal tunnel syndrome symptoms associated to a little painful thenar swelling in the left hand with no motor or sensory deficit. An electromyogram confirmed the clinical diagnosis of carpal tunnel syndrome. Ultrasonography (US), performed to study the thenar swelling, revealed an infracentimetric avascular well-limited intramuscular mass. Surgical resection of the mass was performed satisfactorily with preservation of nerve fascicles. Histopathology concluded to a benign schwannoma of the motor branch of the median nerve. In the literature reviewed by us, this is the third case of motor branch of the median nerve schwannoma.

Keywords

Schwannoma; Motor branch of the median nerve; Tumor; Hand

Introduction

Schwannoma, also called neurilemmoma, is the most frequent benign tumor of the peripheral nerves. It arises from Schwann cells of the nerve sheath. Clinical diagnosis is not always obvious and its non-specific symptoms may lead to a misguided diagnosis, especially when a common hand or wrist pathology is associated. We report a case of schwannoma developing in the motor branch of the median nerve associated to a carpal tunnel syndrome.

Case report

The patient is a 57-year old right-handed woman, with no relevant family or personal history. She presented with a 2- year history of numbness and tingling of both hands, especially noted at night, with a recent weakness of the right hand and pain in the thenar eminence of the left one without motor weakness in the movement of thumb. Physical examination revealed positive Tinel’s test and Phalen’s sign and a painful little solid mass 0.5 cm in the left thenar eminence.

The clinical diagnosis of carpal tunnel syndrome was confirmed by an electromyogram of both upper limbs. Ultrasonography (US) (Figure 1), performed to study the thenar swelling, revealed an avascular well-limited intramuscular mass, communicating to the carpal tunnel by a fistula.

orthopedics-Ultrasound-aspect

Figure 1: Ultrasound aspect of the thenar swelling. An infracentimetric, avascular well-limited intramuscular mass, communicating to the carpal tunnel by a fistula.

Under regional anesthesia and exsanguination with pneumatic tourniquet at the limb, the patient underwent open decompression of the left median nerve with release of the transverse carpal ligament and internal neurolysis. The same palmar incision was used to explore the thenar swelling. Dissection was performed under the radial bank of this incision and intramuscular dissection found a well encapsulated tumor which was intimately associated to the motor branch of the median nerve (Figure 2). Under the 2.5X magnifying loupes, the tumor seems to not involve the fascicles, with the nerve branch being compressed. Microsurgical intracapsular dissection was performed satisfactorily and the mass was marginally resected with preservation of nerve fascicles. A histopathological study concluded to a benign schwannoma of the motor branch of the median nerve.

orthopedics-Intraoperative-views

Figure 2: Intraoperative views. a: well encapsulated tumor intimately associated with the motor branch of the median nerve. b: tumor resection with nerve fascicles preserved.

At 4-month follow-up (Figure 3), the patient reports a total relief from the pain with no signs of complications; nevertheless, an ulterior clinical evaluation is necessary to ensure the absence of recurrence.

orthopedics-thumb-total

Figure 3: four-month follow-up: good opposition of the thumb with total regression of the pain.

Discussion

A schwannoma is a benign neoplastic proliferation of Schwann cells of the nerve sheath [1]. Different body areas can be interested with a predilection for the head and neck area (45% of total schwannomas reported in the literature) [2]. In the extremities, any of the peripheral nerves can be involved but it seems that the peroneal and ulnar nerves are the most frequently affected.

Only 7% of schwannomas arise from the median nerve [3], and its localization in the motor branch is rare. To our knowledge, this is the third case of motor branch of the median nerve schwannoma [4-8].

Grossly, it is a solitary, well-circumscribed fusiforme mass, eccentric to and separate from the adjacent nerve but encapsulated within the perineurium. It can rarely be plexiform [1]. Few cases of multiple schwannomas affecting the same nerve or the same limb have been reported [1,5-7].

Generally, the slow growth pattern of schwannoma allows for adaptation of the nerve fascicles to pressure effects, resulting in a normal motor function, mainly in the first stages. If motor impairment is present, a malignant progression should be highly suspected [9].

Schwannoma can be asymptomatic for long time. But when it arises distal to the wrist, pain becomes the most common symptom with possible paresthesia and hypoanesthesia [8].

In our case, the shared symptoms between schwannoma and carpal tunnel syndrome did not help us to develop the right preoperative diagnostic presumption and ultrasonography was not of great help. Magnetic resonance imaging (MRI) is often indicated to study such masses but it seems that it is not of much help since it cannot reliably distinguish between schwannoma, neurofibroma and malignant peripheralnerve sheath tumors [10].

In our case, like in classic schwannomas, there was a plane of cleavage and the mass was enucleated from the nerve with no damage to the fascicles. In the first case reported by Squarzina et al., this plane of cleavage was not identifiable and the resection sacrificed the motor branch [4].

Conclusion

We present the third case of motor branch of median nerve schwannoma. Preoperative diagnosis can be difficult and multiple differential diagnoses must be considered such as neurofibromatosis, lipofibromatosis, ganglia and soft tissue tumors. Ultrasonography is helpful to differentiate between solid and cystic masses and surgical resection has to preserve nerve fascicles where it’s possible mainly when a motor branch is involved.

References

  1. Cimino-Mathews AM (2011)Peripheral nerve sheath tumors. Surgical Pathology 4: 761–782.
  2. Das Gupta TK, Bras eld RD, Strong EW, Hajdu SI (1969) Benign solitary schwannomas (neurilemomas)Cancer 24:355-366.
  3. Malizos PK, Ioannou M, KontogeorgakosV (2013) Ancient schwannoma involving the median nerve: a case report and review of the literature. StratTraum Limb Recon 8:63–66.
  4. Squarzina PB,Adani R,Cerofolini E,Bagni A,Caroli A (1993) Ancient schwannoma of the motor branch of the median nerve: a clinical case. ChirOrganiMov 78:19-23.
  5. Sarabia JM, Nicolás G, Carrillo FJ (2009) Multiple median nerve schwannoma: a case report. Rev espcirortopTraumatol 53:120-122.
  6. Kato N, Nemoto K, Arino H, Fujikawa K (2002) Multiple neurilemmomas of the median and ulnar nerves with a communicating branch in the same upper extremity (2002). Scand J PlastReconstrSurg Hand Surg 36:314-315.
  7. Talwalkar SC, Cutler L,Stilwell JH (2005) Multipleplexiformschwannoma of the hand and forearm: a long-term follow-up. Journal of Hand Surgery (British and European Volume) 4: 358–360.
  8. Fiaschi P, Pacetti M, Secci F, Gennaro S (2015) A rare case of first motor branch of median nerve Schwannoma NeurolSci 36: 659-661.
  9. Ogose A, Hotta T, Morita T, Yamamura S, Hosaka N, et al. (1999) Tumors of peripheral nerves: correlation of symptoms, clinical signs, imaging features, and histologic diagnosis. Skelet Radiol 28:183–188.
  10. Ahlawat S, Chhabra A,Blakely J (2014) Magnetic Resonance Neurography of Peripheral Nerve Tumors and Tumorlike Conditions. NeuroimagClin N Am 24: 171-192.
Select your language of interest to view the total content in your interested language

Viewing options

Post your comment

Share This Article

Flyer image
 

Post your comment

captcha   Reload  Can't read the image? click here to refresh